Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Is Inactivation of the X Chromosome in the Female Mule Non-random?

Abstract

HAMERTON et al.1 have presented evidence which they interpret as a demonstration of preferential late replication of the donkey X chromosome (paternal X) in the female mule complement. This is in disagreement with cytological evidence2 for random X-inactivation3 in the female mule complement. This apparent contradiction prompted us to repeat the latter study and we report here our observations.

Access to this article via ICE Institution of Civil Engineers is not available.

This is a preview of subscription content, access via your institution

Access options

Access to this article via ICE Institution of Civil Engineers is not available.

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hamerton, J. L., Giannelli, F., Collins, F., Hallett, J., Frayer, A., and McGuire, V. M., Natare, 222, 1277 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Mukherjee, B. B., and Sinha, A. K., Proc. US Nat. Acad. sci., 51, 252 (1964).

    Article  ADS  CAS  Google Scholar 

  3. Lyon, M. F., Amer. J. Human Genet., 14, 135 (1962).

    CAS  Google Scholar 

  4. Trujillo, J. M., Stenis, C., Christian, L. C., and Ohno, S., Chromosoma, 13, 243 (1962).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MUKHERJEE, B., MUKHERJEE, A. & MUKHERJEE, A. Is Inactivation of the X Chromosome in the Female Mule Non-random?. Nature 228, 1321–1322 (1970). https://doi.org/10.1038/2281321a0

Download citation

  • Received:

  • Issue date:

  • DOI: https://doi.org/10.1038/2281321a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing