Abstract
It is proposed that random genetic drift of neutral mutations in finite populations can account for observed protein polymorphisms.
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References
Kimura, M., Nature, 217, 624 (1968).
King, J. L., and Jukes, T. H., Science, 164, 788 (1969).
Crow, J. F., Proc. Twelfth Intern. Cong. Genet., 3, 105 (1969).
Arnheim, N., and Taylor, C. E., Nature, 223, 900 (1969).
Kimura, M., Proc. US Nat. Acad. Sci., 63, 1181 (1969).
Maynard Smith, J., Nature, 219, 1114 (1968).
Richmond, R. C., Nature, 225, 1025 (1970).
Clarke, B., Science, 168, 1009 (1970).
Kimura, M., and Ohta, T., J. Mol. Evol. (in the press).
Lewontin, R. C., and Hubby, J. L., Genetics, 54, 595 (1966).
Harris, H., Proc. Roy. Soc.B, 164, 298 (1966).
Prakash, S., Lewontin, R. C., and Hubby, J. L., Genetics, 61, 841 (1969).
Petras, M. L., Reimer, J. D., Biddle, F. G., Martin, J. E., and Linton, R. S., Canad. J. Genet. Cytol., 11, 497 (1969).
Maynard Smith, J., Amer. Nat., 104, 231 (1970).
Robertson, S., in Population Biology and Evolution (edit. by Lewontin, R.), 5 (Syracuse University Press, New York, 1968).
Haga, T., and Kurabayashi, M., Cytologia, 18, 13 (1953).
Haga, T., in Chromosomes Today, 2 (edit. by Darlington, C. D., and Lewis, K. R.), 207 (1969).
Wright, S., Annals of Eugenics, 15, 323 (1951).
Maruyama, T., Theoretical Population Biology, 1, 101 (1970).
Maruyama, T., Japan. J. Genet. (in the press).
Kimura, M., and Crow, J. F., Genetics, 49, 725 (1964).
Kimura, M., Theoretical Population Biology (in the press).
Selander, R. K., Yang, S. Y., Lewontin, R. C., and Johnson, W. E., Evolution, 24, 402 (1970).
Kimura, M., and Ohta, T., Genetics, 61, 763 (1969).
Kimura, M., Proc. US Nat. Acad. Sci., 41, 144 (1955).
Ohta, T., and Kimura, M., Genet. Res. (in the press).
Selander, R. K., Hunt, W. G., and Yang, S. Y., Evolution, 23, 379 (1969).
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KIMURA, M., OHTA, T. Protein Polymorphism as a Phase of Molecular Evolution. Nature 229, 467–469 (1971). https://doi.org/10.1038/229467a0
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DOI: https://doi.org/10.1038/229467a0
