Pharmaceutical Sciences PhD Candidate at the University of North Carolina at Chapel Hill. Anticipated graduation is August 2026.

Abigail Klein Mayo | Linktree

A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity - PubMed

The elucidation of species-specific receptor pharmacology: A case study using subtype-selective para- and meta-carborane estrogen receptor agonists - PubMed

Species-Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with In Vivo Antialphaviral Activity - PubMed

OSU-ERβ-12: a promising pre-clinical candidate selective estrogen receptor beta agonist - PubMed

I am a PhD candidate in the Division of Pharmacotherapy and Experimental Therapeutics under the mentorship of Dr. Kim Brouwer. My research includes wet lab experimentation and in silico methodologies, like quantitative systems toxicology modeling. My focus areas are liver transporters, liver disease, and mechanisms of liver injury, with applications in drug development.

I have extensive experience in primary and cell line culture and a range of endpoint and functional assays, including western blotting, immunocytochemistry/ image analysis, qPCR, and functional assays including B-CLEAR. I have also contributed pharmacokinetic analyses through collaborations supporting novel therapeutics.

I am adaptable and resilient, with experience in teaching, scientific presentation, and mentoring. My scholarly work includes presentations and peer-reviewed publications (see CV), as well as a first-author manuscript under review and a forthcoming book chapter on Drug Transporters in Liver Disease. 

About my research

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Abigail Mayo CV

Publications

Abigail Klein Mayo

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