Package: metalite.ae 0.1.3

Yujie Zhao

metalite.ae: Adverse Events Analysis Using 'metalite'

Analyzes adverse events in clinical trials using the 'metalite' data structure. The package simplifies the workflow to create production-ready tables, listings, and figures discussed in the adverse events analysis chapters of "R for Clinical Study Reports and Submission" by Zhang et al. (2022) <https://r4csr.org/>.

Authors:Yilong Zhang [aut], Yujie Zhao [aut, cre], Benjamin Wang [aut], Nan Xiao [aut], Sarad Nepal [aut], Madhusudhan Ginnaram [aut], Venkatesh Burla [ctb], Ruchitbhai Patel [aut], Brian Lang [aut], Xuan Deng [aut], Hiroaki Fukuda [aut], Bing Liu [aut], Jeetender Chauhan [aut], Li Ma [ctb], Merck Sharp & Dohme Corp [cph]

metalite.ae_0.1.3.tar.gz
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metalite.ae_0.1.3.tgz(r-4.6-any)metalite.ae_0.1.3.tgz(r-4.5-any)
metalite.ae_0.1.3.tar.gz(r-4.6-any)metalite.ae_0.1.3.tar.gz(r-4.5-any)
metalite.ae_0.1.3.tgz(r-4.5-emscripten)
metalite.ae.pdf |metalite.ae.html✨
metalite.ae/json (API)
NEWS

# Install 'metalite.ae' in R:
install.packages('metalite.ae', repos = c('https://merck.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/merck/metalite.ae/issues

Pkgdown/docs site:https://merck.github.io

Datasets:

On CRAN:

Conda:

cdiscclinical-trialsmetadata

9.24 score 25 stars 2 packages 34 scripts 770 downloads 26 exports 57 dependencies

Last updated from:7351dc66a2. Checks:6 NOTE, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64NOTE224
source / vignettesOK232
linux-release-x86_64NOTE214
macos-devel-arm64NOTE162
macos-release-arm64NOTE134
windows-develNOTE173
windows-releaseNOTE170
wasm-releaseOK132

Exports:extend_ae_specific_durationextend_ae_specific_eventsextend_ae_specific_inferenceextend_ae_specific_subgroupextend_ae_summary_eaerfmt_cifmt_estfmt_pctfmt_pvalformat_ae_exp_adjformat_ae_specificformat_ae_specific_subgroupformat_ae_summarygt_ae_summarymeta_ae_exampleprepare_ae_listingprepare_ae_specificprepare_ae_specific_subgroupprepare_ae_summaryrate_comparerate_compare_sumtlf_ae_exp_adjtlf_ae_listingtlf_ae_specifictlf_ae_specific_subgrouptlf_ae_summary

Dependencies:base64encbigDbitopsbslibcachemclicommonmarkcurldigestdplyrevaluatefarverfastmapfontawesomefsgenericsgluegthighrhtmltoolshtmlwidgetsjquerylibjsonlitejuicyjuiceknitrlabelinglifecyclelitedownmagrittrmarkdownmemoisemetalitemimepillarpkgconfigr2rtfR6rappdirsRColorBrewerRcppreactablereactRrlangrmarkdownsassscalestibbletidyselecttinytexutf8V8vctrsviridisLitewithrxfunxml2yaml

Add Term1 and Term2 Example

Rendered fromadd-term1-term2-example.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2025-09-26
Started: 2025-09-26

AE Listing

Rendered fromae-listing.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-11-18
Started: 2022-11-01

AE Specification

Rendered fromae-specific.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-11-18
Started: 2022-04-19

AE Summary

Rendered fromae-summary.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-11-18
Started: 2022-04-19

Exposure Adjusted Event Rate

Rendered fromexposure-adjusted-event-rate.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-04-08
Started: 2023-08-03

Introduction to metalite.ae

Rendered frommetalite-ae.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-11-18
Started: 2022-04-19

Subgroup Analysis for Specific AE

Rendered fromae-specific-subgroup.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2024-11-18
Started: 2023-08-24

Unstratified and Stratified Miettinen and Nurminen Test

Rendered fromrate-compare.Rmdusingknitr::rmarkdownon Mar 24 2026.

Last update: 2023-02-19
Started: 2022-04-19

Readme and manuals

Help Manual

Help pageTopics
Add average duration information for AE specific analysisextend_ae_specific_duration
Add average number of events information for AE specific analysisextend_ae_specific_events
Add inference information for AE specific analysisextend_ae_specific_inference
Add subgroup analysis in AE specific analysisextend_ae_specific_subgroup
Add exposure-adjusted rate information for AE summary analysisextend_ae_summary_eaer
Format confidence intervalfmt_ci
Format model estimatorfmt_est
Format percentagefmt_pct
Format p-valuefmt_pval
Format exposure-adjusted AE summaryformat_ae_exp_adj
Format AE specific analysisformat_ae_specific
Format AE specific subgroup analysisformat_ae_specific_subgroup
Format AE summary analysisformat_ae_summary
AE summary tablegt_ae_summary
Create an example 'meta_adam' objectmeta_ae_example
ADEX datasetmetalite_ae_adex
ADEXSUM datasetmetalite_ae_adexsum
Prepare datasets for AE listingprepare_ae_listing
Prepare datasets for AE specific analysisprepare_ae_specific
Prepare datasets for AE specific subgroup analysisprepare_ae_specific_subgroup
Prepare datasets for AE summaryprepare_ae_summary
Unstratified and stratified Miettinen and Nurminen testrate_compare
Unstratified and stratified Miettinen and Nurminen test in aggregate data levelrate_compare_sum
Exposure-adjusted AE summary tabletlf_ae_exp_adj
Generate AE listingtlf_ae_listing
Specific adverse events tabletlf_ae_specific
Specific adverse events table for subgroup analysistlf_ae_specific_subgroup
AE summary tabletlf_ae_summary