OpenAI and Molecule.one show how a near-autonomous AI chemist using GPT-5.4 improved a key drug-making reaction, advancing medicinal chemistry research.

Introducing LifeSciBench, an expert-authored, expert-reviewed benchmark for evaluating how AI systems handle real-world life science research tasks and decisions.

ChatGPT introduces a new memory system to better remember preferences, keeping context fresh and relevant across conversations.

GPT-Rosalind advances life sciences research with enhanced biological reasoning, medicinal chemistry expertise, genomics analysis, and experimental workflow capabilities.

OpenAI launches Rosalind Biodefense, expanding trusted access to GPT-Rosalind for vetted developers and U.S. government partners advancing biodefense, public health, and pandemic preparedness through frontier AI.

An OpenAI model solved the 80-year-old unit distance problem, disproving a major conjecture in discrete geometry and marking a milestone in AI-driven mathematics.

Explore new realtime voice models in the OpenAI API that can reason, translate, and transcribe speech, enabling more natural and intelligent voice experiences.

GPT-5.5 Instant updates ChatGPT’s default model with smarter, more accurate answers, reduced hallucinations, and improved personalization controls.