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Case Reports
. 2013 Dec 16;19(12):20709.

Necrolytic acral erythema

John Montgomery Yost  1 , Kevin P Boyd, Rishi R Patel, Sarika Ramachandran, Andrew G Franks Jr
Affiliations
  • PMID: 24365000
Free article
Case Reports

Necrolytic acral erythema

John Montgomery Yost et al. Dermatol Online J. .
Free article

Abstract

Necrolytic acral erythema is a rare, cutaneous manifestation of hepatitis C virus infection that is characterized by erythematous, violaceous or dusky papules, blisters, and/or erosions in the early stages and by well-demarcated, hyperkeratotic, targetoid plaques with a peripheral rim of macular erythema, secondary lichenification and hyperpigmentation, and overlying fine micaceous or necrotic-appearing scale in the later stages. Because most topical modalities prove ineffective, treatment of the underlying viral infection or therapeutic zinc supplementation are required for clinical improvement.

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