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. 2017 Dec;53(6S2):S121-S130.
doi: 10.1016/j.amepre.2017.05.008.

A Systematic Review of Economic Evidence on Community Hypertension Interventions

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A Systematic Review of Economic Evidence on Community Hypertension Interventions

Donglan Zhang et al. Am J Prev Med. 2017 Dec.

Abstract

Context: Effective community-based interventions are available to control hypertension. It is important to determine the economics of these interventions.

Evidence acquisition: Peer-reviewed studies from January 1995 through December 2015 were screened. Interventions were categorized into educational interventions, self-monitoring interventions, and screening interventions. Incremental cost-effectiveness ratios were summarized by types of interventions. The review was conducted in 2016.

Evidence synthesis: Thirty-four articles were included in the review (16 from the U.S., 18 from other countries), including 25 on educational interventions, three on self-monitoring interventions, and six on screening interventions. In the U.S., five (31.3%) studies on educational interventions were cost saving. Among the studies that found the interventions cost effective, the median incremental costs were $62 (range, $40-$114) for 1-mmHg reduction in systolic blood pressure (SBP) and $13,986 (range, $6,683-$58,610) for 1 life-year gained. Outside the U.S., educational interventions cost from $0.62 (China) to $29 (Pakistan) for 1-mmHg reduction in SBP. Self-monitoring interventions, evaluated in the U.S. only, cost $727 for 1-mmHg reduction in SBP and $41,927 for 1 life-year gained. For 1 quality-adjusted life-year, screening interventions cost from $21,734 to $56,750 in the U.S., $613 to $5,637 in Australia, and $7,000 to $18,000 in China. Intervention costs to reduce 1 mmHg blood pressure or 1 quality-adjusted life-year were higher in the U.S. than in other countries.

Conclusions: Most studies found that the three types of interventions were either cost effective or cost saving. Quality of economic studies should be improved to confirm the findings.

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Figures

Figure 1
Figure 1
Selection of cost-effectiveness literature on community-based interventions for hypertension control based on PRISMA flow diagram, 1995–2015. Note: Searched key words: (1) Interventions: “community health worker” or “community-based” or “community-based interventions” “community-clinical coordination” or “outreach services” or “culturally competent services” or “promoters” or “community health education.” (2) Outcomes: “hypertension” or “high blood pressure” or “diastolic” “systolic” or “Quality adjusted life years” or “QALYs” or “life years gained” or “disability-adjusted life years” or “DALYs” or “adherence to anti-hypertensive medication.” (3) Study type: “Cost-benefit” or “cost-effectiveness” or “cost-utility” or “economic evaluation” or “budget impact analysis.”

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