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Clinical Trial
. 2020 Feb;188(3):e18-e21.
doi: 10.1111/bjh.16272. Epub 2019 Nov 11.

Safety and effectiveness of thalidomide and hydroxyurea combination in β-thalassaemia intermedia and major: a retrospective pilot study

Sandip Shah  1 , Radhika Sheth  1 , Kamlesh Shah  2 , Kinnari Patel  2
Affiliations
Clinical Trial

Safety and effectiveness of thalidomide and hydroxyurea combination in β-thalassaemia intermedia and major: a retrospective pilot study

Sandip Shah et al. Br J Haematol. 2020 Feb.
No abstract available

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References

    1. Aerbajinai, W., Zhu, J., Gao, Z., Chin, K. & Rodgers, G.P. (2007) Thalidomide induces γ-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis. Blood, 8, 2864-2871.
    1. Angelucci, E., Matthes-Martin, S., Baronciani, D., Bernaudin, F., Bonanomi, S., Cappellini, M.D., Dalle, J.-H., Di Bartolomeo, P., de Heredia, C.D., Dickerhoff, R., Giardini, C., Gluckman, E., Hussein, A.A., Kamani, N., Minkov, M., Locatelli, F., Rocha, V., Sedlacek, P., Smiers, F., Thuret, I., Yaniv, I., Cavazzana, M. & Peters, C. (2014) Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel. Haematologica, 5, 811-820.
    1. de Dreuzy, E., Bhukhai, K., Leboulch, P. & Payen, E. (2016) Current and future alternative therapies for beta-thalassemia major. Biomedical Journal, 1, 24-38.
    1. Galanello, R. & Origa, R. (2010) Beta-thalassemia. Orphanet Journal of Rare Diseases, 1, 11.
    1. Gambari, R. (2010) Foetal haemoglobin inducers and thalassaemia: novel achievements. Blood Transfusion, 1, 5-7.

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