Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1997 Sep 20;102(2):291-3.
doi: 10.1016/s0165-3806(97)00090-4.

Increased beta adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonin depletion

P E Langdon  1 , C W Harley, J H McLean
Affiliations
Comparative Study

Increased beta adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonin depletion

P E Langdon et al. Brain Res Dev Brain Res. .

Abstract

It was hypothesized that 5-HT2 receptors in the olfactory bulb prime the bulbar response to a beta adrenoceptor mediated unconditioned stimulus (UCS) during odor preference learning in 1-week-old rat pups. The ability of 4 mg/kg of isoproterenol + stroking and 6 mg/kg of isoproterenol + no stroking to induce normal odor preference learning in pups depleted of bulbar 5-HT in the present study supports the hypothesis. The inverted-U curve relation between UCS strength and learning also appears to occur within the bulb.

PubMed Disclaimer

Publication types

LinkOut - more resources