2015
DOI: 10.1186/s12970-015-0090-y
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International society of sports nutrition position stand: Beta-Alanine

Abstract: Position statementThe International Society of Sports Nutrition (ISSN) provides an objective and critical review of the mechanisms and use of beta-alanine supplementation. Based on the current available literature, the conclusions of the ISSN are as follows: 1) Four weeks of beta-alanine supplementation (4–6 g daily) significantly augments muscle carnosine concentrations, thereby acting as an intracellular pH buffer; 2) Beta-alanine supplementation currently appears to be safe in healthy populations at recomme… Show more

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Cited by 263 publications

(302 citation statements)
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“…In contrast to the results of previous investigations [8], no effect of beta-alanine was found on anaerobic performance, blood lactate responses, heart rate responses, or RPE during recovery. However, it is important to note that a beta-alanine exerted large but non-significant effects on recovery blood lactate ( d = −0.94) and recovery RPE ( d = −1.23), suggesting that the supplement may have some degree of practical benefit for acute recovery following anaerobic exercise.…”
Section: Discussioncontrasting
confidence: 99%
“…Overall, beta-alanine’s ability to exert ergogenic outcomes on maximal strength and repetitions to fatigue appears limited as changes in strength, endurance, and power were lacking. These results fall in line with previous observations, as several studies have generally failed to report ergogenic outcomes in these parameters following beta-alanine supplementation [8]. Further, this pilot investigation suggested a limited potential for beta-alanine to improve muscular endurance.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…In contrast to the results of previous investigations [8], no effect of beta-alanine was found on anaerobic performance, blood lactate responses, heart rate responses, or RPE during recovery. However, it is important to note that a beta-alanine exerted large but non-significant effects on recovery blood lactate ( d = −0.94) and recovery RPE ( d = −1.23), suggesting that the supplement may have some degree of practical benefit for acute recovery following anaerobic exercise.…”
Section: Discussioncontrasting
confidence: 99%
“…Overall, beta-alanine’s ability to exert ergogenic outcomes on maximal strength and repetitions to fatigue appears limited as changes in strength, endurance, and power were lacking. These results fall in line with previous observations, as several studies have generally failed to report ergogenic outcomes in these parameters following beta-alanine supplementation [8]. Further, this pilot investigation suggested a limited potential for beta-alanine to improve muscular endurance.…”
Section: Discussionsupporting
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Succinate, which is converted from succinic acid, has been identi ed to play a role in regulating skeletal muscle remodelling 21 . β-alanine was highly abundant within our dataset; a compound largely synthesised in the liver of living organisms, and therefore predominantly found in meat 45 which was in line with our data (most abundant in pork and salmon) (Fig. 3.).…”
Section: Discussionsupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…However, the primary finding of this study indicates that βA does not appear to offer significant benefits to sustained endurance performance, as assessed via a 30-min time trial when compared to placebo. These findings concur with an earlier 2015 ISSN Position Stand [14] indicating that βA consumption “does not demonstrate a consistent positive effect” on events lasting beyond a 25-min timeframe. It is, however, noteworthy that within-group improvements were observed for mean distance covered, average power and average power to weight ratio when participants consumed βA daily, increasing by 2.6, 14.6 and 14.9%, respectively over the intervention period.…”
Section: Discussionsupporting
confidence: 90%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.