Taurine does not affect the composition, diversity, or metabolism of human colonic microbiota simulated in a single-batch fermentation system

Sasaki, Kengo; Sasaki, Daisuke; Okai, Naoko; Tanaka, Kosei; Nomoto, Ryohei; Fukuda, Itsuko; Yoshida, Ken‐ichi; Kondo, Akihiko; Osawa, Ro

doi:10.1371/journal.pone.0180991

PLoS ONE

2017

DOI: 10.1371/journal.pone.0180991

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Taurine does not affect the composition, diversity, or metabolism of human colonic microbiota simulated in a single-batch fermentation system

Kengo Sasaki

¹

,

Daisuke Sasaki

²

,

Naoko Okai

³

et al.

Abstract: Accumulating evidence suggests that dietary taurine (2-aminoethanesulfonic acid) exerts beneficial anti-inflammatory effects in the large intestine. In this study, we investigated the possible impact of taurine on human colonic microbiota using our single-batch fermentation system (Kobe University Human Intestinal Microbiota Model; KUHIMM). Fecal samples from eight humans were individually cultivated with and without taurine in the KUHIMM. The results showed that taurine remained largely undegraded after 30 h … Show more

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Cited by 22 publications

(17 citation statements)

References 47 publications

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“…The results of the present experiment also showed that dietary supplementation with taurine did not affect the ruminal pH, concentrations of NH 3 ‐N and VFA or the molar proportions of individual VFA. The results were in agreement with a previous study in which human fecal samples cultivated with taurine did not affect the composition of short‐chain fatty acids produced in the cultures 29 . The reason for the results could be that most of the taurine was hydrolyzed and the amount of unhydrolyzed taurine was not sufficient to impact the rumen fermentation parameters.…”

Section: Discussionsupporting

confidence: 91%

“…The results were in agreement with a previous study in which human fecal samples cultivated with taurine did not affect the composition of short-chain fatty acids produced in the cultures. 29 The reason for the results could be that most of the taurine was hydrolyzed and the amount of unhydrolyzed taurine was not sufficient to impact the rumen fermentation parameters.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of taurine on rumen fermentation, nutrient digestion, rumen bacterial community and metabolomics and nitrogen metabolism in beef steers

Liu

¹

,

Hu

²

,

Li

³

et al. 2023

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…The results of the present experiment also showed that dietary supplementation with taurine did not affect the ruminal pH, concentrations of NH 3 ‐N and VFA or the molar proportions of individual VFA. The results were in agreement with a previous study in which human fecal samples cultivated with taurine did not affect the composition of short‐chain fatty acids produced in the cultures 29 . The reason for the results could be that most of the taurine was hydrolyzed and the amount of unhydrolyzed taurine was not sufficient to impact the rumen fermentation parameters.…”

Section: Discussionsupporting

confidence: 91%

“…The results were in agreement with a previous study in which human fecal samples cultivated with taurine did not affect the composition of short-chain fatty acids produced in the cultures. 29 The reason for the results could be that most of the taurine was hydrolyzed and the amount of unhydrolyzed taurine was not sufficient to impact the rumen fermentation parameters.…”

Section: Discussionmentioning

confidence: 99%

Effects of taurine on rumen fermentation, nutrient digestion, rumen bacterial community and metabolomics and nitrogen metabolism in beef steers

Liu

¹

,

Hu

²

,

Li

³

et al. 2023

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…The dramatic expansion of Proteobacteria during the batch fermentation experiments has already been reported by others (Takagi et al, 2016;Sasaki et al, 2017;O'Donnell et al, 2018;Wiese et al, 2018). Higher relative abundances of Proteobacteria were obtained after 24 h of fermentation in our study compared to batch fermentation experiments performed which the same mGAM culture medium and in the same pH conditions (Takagi et al, 2016).…”

Section: Discussionsupporting

confidence: 84%

Assessment of Gram- and Viability-Staining Methods for Quantifying Bacterial Community Dynamics Using Flow Cytometry

Duquenoy

¹

,

Bellais

²

,

Gasc

³

et al. 2020

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…We found that acetic acid was found in the majority of these samples, but propionic acid and butanoic acid were not. Studies on the fermentation of taurine have shown that acetic acid is the most common short-chain fatty acid (SCFA) derived from this amino acid [ 13 ]: it is plausible that the taurine-rich amniotic fluid is responsible for this pattern of SCFA in the meconium.…”

Section: Discussionmentioning

confidence: 99%

The Stool Volatile Metabolome of Pre-Term Babies

Frau

¹

,

Lett

²

,

Slater

³

et al. 2021

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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