Anaerobe
 2018
DOI: 10.1016/j.anaerobe.2018.05.009
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Molecular epidemiology of Clostridioides (Clostridium) difficile strains recovered from clinical trials in the US, Canada and Europe from 2006-2009 to 2012-2015

Adam Cheknis
1
,
Stuart Johnson
2
,
Laurent Chesnel
3
et al.
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Cited by 29 publications

(17 citation statements)
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“…Most prominent among binary toxin-negative strains were ST2/13(RT014/020), ST8(RT002), ST6(RT005/117), ST14/49(RT014), ST12/54/139(RT012) and ST3(RT001), consistent with several studies from Europe [18][19][20][21], Sweden [22,23], Scotland [24], the US [25][26][27], worldwide [28] and Australia [29]. ST2/13(RT014/020) accounted for 19.5% of all isolates, and several other studies have found this type predominant and often associated with a community acquired origin [27,29].…”
Section: Discussionsupporting
confidence: 89%
“…Most prominent among binary toxin-negative strains were ST2/13(RT014/020), ST8(RT002), ST6(RT005/117), ST14/49(RT014), ST12/54/139(RT012) and ST3(RT001), consistent with several studies from Europe [18][19][20][21], Sweden [22,23], Scotland [24], the US [25][26][27], worldwide [28] and Australia [29]. ST2/13(RT014/020) accounted for 19.5% of all isolates, and several other studies have found this type predominant and often associated with a community acquired origin [27,29]. A recent Danish study found this type common among dog faeces collected from rubbish bins in public parks in Copenhagen, and closely related (cgMLST) to human clinical isolates collected from the same area during the same time period [30].…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Most prominent among binary toxin-negative strains were ST2/13(RT014/020), ST8(RT002), ST6(RT005/117), ST14/49(RT014), ST12/54/139(RT012) and ST3(RT001), consistent with several studies from Europe [18][19][20][21], Sweden [22,23], Scotland [24], the US [25][26][27], worldwide [28] and Australia [29]. ST2/13(RT014/020) accounted for 19.5% of all isolates, and several other studies have found this type predominant and often associated with a community acquired origin [27,29].…”
Section: Discussionsupporting
confidence: 89%
“…Most prominent among binary toxin-negative strains were ST2/13(RT014/020), ST8(RT002), ST6(RT005/117), ST14/49(RT014), ST12/54/139(RT012) and ST3(RT001), consistent with several studies from Europe [18][19][20][21], Sweden [22,23], Scotland [24], the US [25][26][27], worldwide [28] and Australia [29]. ST2/13(RT014/020) accounted for 19.5% of all isolates, and several other studies have found this type predominant and often associated with a community acquired origin [27,29]. A recent Danish study found this type common among dog faeces collected from rubbish bins in public parks in Copenhagen, and closely related (cgMLST) to human clinical isolates collected from the same area during the same time period [30].…”
Section: Discussionsupporting
confidence: 89%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…In contrast, the opposite order was seen among CA-CDI isolates, where ST2 was the most detected strain, followed by ST42. Several studies suggested that RT014/RT020/ST2 has a community origin (25,26), a hypothesis that was strengthened by the current results. Furthermore, RT014/ST2 isolates have been recovered from various environmental sources including wastewater (27), parks and homes (28), another strengthening evidence for a community origin for this strain.…”
Section: Discussionsupporting
confidence: 78%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…This observation was reversed for clade 1, which was more prevalent inland [ 101 ]. Another recent study [ 94 ] focusing on stool specimens recovered from 2011 to 2016 in the states of Illinois, Minnesota, New York, Massachusetts, California, and Virginia showed a marked decrease in the prevalence of RT027 over these six years in agreement with what was seen in Europe and Canada [ 94 , 112 , 115 , 116 , 117 , 118 ]. This decrease was also found in a 2020 study [ 119 ], covering the 2011–2018 period in Texas, where the most common RT was RT027, followed by RT014-020, RT106, and RT002.…”
Section: Worldwide Distribution Of C Difficile Rib...supporting
confidence: 62%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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