2018
Dietary Sodium to Potassium Ratio and the Incidence of Chronic Kidney Disease in Adults : A Longitudinal Follow-Up Study
Abstract: The aim of this study was to explore the association of dietary sodium to potassium (Na/K) ratio and the risk of chronic kidney disease (CKD) in general Iranian adults. In this prospective cohort study, 1,780 adults, free of baseline CKD with complete follow-up data, were selected from among participants of the Tehran Lipid and Glucose Study and followed for 6.3 years for development of CKD. Dietary sodium and potassium were assessed using a valid and reliable 168-item food frequency questionnaire. Estimated g…
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Cited by 26 publications
(24 citation statements)
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“…Furthermore, a meta-analysis of population Na intake showed a "U shape" relationship with the risk of mortality [ 55 ], and mean estimated Na intake was inversely associated with mortality at a level of < 4 g/d (10 g/d salt) [ 41 ]. Previous studies among our population also showed no significant association between dietary intake of Na and the risk of hypertension, CVD, and renal dysfunction [ 56 , 57 ]. Current evidence relating Na intake to hypertension and CVD has significant limitations [ 9 ] and could not provide a strong statement on the adverse effect of Na intake on CVD outcomes and all-cause mortality [ 58 ].…”
Section: Discussionsupporting
confidence: 40%
“…Furthermore, a meta-analysis of population Na intake showed a "U shape" relationship with the risk of mortality [ 55 ], and mean estimated Na intake was inversely associated with mortality at a level of < 4 g/d (10 g/d salt) [ 41 ]. Previous studies among our population also showed no significant association between dietary intake of Na and the risk of hypertension, CVD, and renal dysfunction [ 56 , 57 ]. Current evidence relating Na intake to hypertension and CVD has significant limitations [ 9 ] and could not provide a strong statement on the adverse effect of Na intake on CVD outcomes and all-cause mortality [ 58 ].…”
Section: Discussionsupporting
confidence: 40%
“…The ratio Na/K is very important in the human health due to the sodium intake, and the increase of the potassium intake might reduce cardiovascular events and prevent the onset of hypertension. 55 This is due to the fact that the increase in potassium absorption in the gastrointestinal tract is accompanied by a decrease in sodium absorption. 56 The potassium/sodium ratio recommended is 0.5 for an average diet.…”
Section: Resultsmentioning
confidence: 99%
“…Sodium (Na) and calcium (Ca) were detected with similar portions between them and with slight value variations among the drying techniques applied. The ratio Na/K is very important in the human health due to the sodium intake, and the increase of the potassium intake might reduce cardiovascular events and prevent the onset of hypertension . This is due to the fact that the increase in potassium absorption in the gastrointestinal tract is accompanied by a decrease in sodium absorption .…”
Section: Resultsmentioning
confidence: 99%
“…The result indicated that Vitex doniana leaves had low sodium/potassium ratio (0.047) and relatively high calcium/phosphorus ratio (1.43). Sodium/potassium ratio is associated with blood pressure (BP) in humans [29] [30] [31] [32]. High sodium and potassium intake are known to be related to high and low blood pressure, respectively [33] [34] [35].…”
Section: Resultsmentioning
confidence: 99%
