Key takeaways

  • Hereditary transthyretin amyloid cardiomyopathy (hATTR-CM) affects your heart’s ability to pump blood and may cause several symptoms, including fatigue.
  • Getting enough sleep, resting when you need to, and avoiding alcohol and caffeine may help reduce the fatigue you might experience with this condition.
  • Drinking enough water is also important for managing fatigue, but the definition of “enough” varies because some people with hATTR-CM need to limit fluids. Talk with your doctor about the right fluid intake for you.

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an often-overlooked heart disorder that involves the buildup of protein deposits within the heart muscle. When the condition is caused by an inherited gene variant, it’s called hereditary transthyretin amyloid cardiomyopathy (hATTR-CM).

The buildup of proteins stiffens the heart muscle, making it more difficult for the heart to pump blood. As a result, if you live with hATTR-CM, you may experience symptoms such as fatigue, shortness of breath, and reduced exercise tolerance. Fatigue may also occur as a side effect of medications you take to treat the condition.

Research suggests that fatigue is one of the most challenging symptoms of ATTR-CM. But there are steps you can take to cope with fatigue and stay active while living with this condition.

Review the graphic below to learn about 6 ways you can manage fatigue in hATTR-CM.