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Exclusive: Start-up FutureHouse debuts powerful AI ‘reasoning model’ for science

The model, called ether0, outperforms other advanced AIs at chemistry tasks and is a stepping stone towards automating the entire research pipeline.
By
  1. Zack Savitsky

As artificial intelligence (AI) tools shake up the scientific workflow, Sam Rodriques dreams of a more systemic transformation. His start-up company, FutureHouse in San Francisco, California, aims to build an ‘AI scientist’ that can command the entire research pipeline, from hypothesis generation to paper production.

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Nature 642, 552-553 (2025)

doi: https://doi.org/10.1038/d41586-025-01753-1

References

  1. Ghareeb, A. E. et al. Preprint at arXiv https://doi.org/10.48550/arXiv.2505.13400 (2025).

  2. Mirza, A. et al. Nature Chem. https://doi.org/10.1038/s41557-025-01815-x (2025).

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  3. Messeri, L. & Crockett, M. J. Nature 627, 49–58 (2024).

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