Contact resistance limits device performance. Here, the authors fabricate a strong yet highly conductive liquid-metal-bridged nanogranular composite via friction induced in-situ synthesis, achieving low contact resistivity and high current density.

Eutectic gallium indium is proposed to address the challenge of integrating infrared camouflage with self-powered thermoelectric sensing, enabling simultaneous concealment of thermal signatures and real-time physiological monitoring without complex fabrication.

Atomically precise metal clusters that combine structural clarity, functional modularity, and spatial programmability are becoming increasingly relevant. Here, the authors report the synthesis and applications of the cluster-based Au₈Pd₁(DPPF)₄²⁺/Al₂O₃ catalyst for hydrogen peroxide generation.

Light alkanes offer a route to key aromatics, but controlling competing catalytic steps remains difficult. This study separates and matches reaction stages to boost benzene, toluene and xylene production.

Authors present an ErCl₃-catalyzed cyanation of both aliphatic and aryl ketone hydrazones for the facile access of C(alpha)-tetrasubstituted alpha-hydrazino nitriles in up to 96% ee, by using a sterically confined pyridinebisoxazoline (PYBOX) ligand featuring a sulfonyl group at the pyridine C4 position.

Researchers reveal microbial metabolic pathways driving high levels of a climate-relevant sulfur compound in Antarctic sea ice and identify key microbes that may shape sulfur cycling and climate feedbacks in the Southern Ocean.

This study finds that ancient methane from deep-sea sediments can be trapped as organic carbon in the seafloor’s top layer, highlighting an overlooked ocean carbon sink, which helps to reduce greenhouse gas release from the seafloor.

A global analysis of over 7,000 climate-related disasters shows that human development is a stronger determinant of local disaster impacts than hazard intensity, and that inequality in human development amplifies risk in the least developed regions.

National-level technology diffusion rates vary substantially across 130 technologies and 5,990 time series. Newer technologies, as well as smaller, less materially intensive, and shorter-lived technologies, tend to be adopted more quickly.

Diesel use in remote Arctic communities could be reduced with hydrokinetic river turbines. The study identifies 325 viable communities globally and confirms feasibility in Nunavut, Canada, highlighting strong potential for cleaner local energy.

PASTA-kinases govern the bacterial cell cycle. Here, authors solve the structure of the catalytic domain of the protein kinase StkP from Streptococcus pneumoniae and provide a mechanistic framework for its activation and regulation.

Nanopore sensing struggles to resolve structurally similar molecules from noisy temporal signals. Here, authors present SEDA-Former, which integrates multi-scale temporal enhancement and progressive adaptive attention training, to achieve robust and accurate classification across diverse molecular datasets.

How metastatic progenitor cells emerge and persist remains to be understood. Here the authors show that in lung adenocarcinoma progenitors, the cell adhesion molecule L1CAM drives SOX2 expression via the planar cell polarity complex to sustain regenerative and metastatic capacity.

Researchers reveal microbial metabolic pathways driving high levels of a climate-relevant sulfur compound in Antarctic sea ice and identify key microbes that may shape sulfur cycling and climate feedbacks in the Southern Ocean.

Biological valorization of lignin is hindered by substrate toxicity and metabolism inefficiency. Here, the authors established a platform for lignin-derived aromatics tolerance engineering and multi-node dynamic pathway control in Corynebacterium glutamicum.

South Asian populations remain underrepresented in cancer genomics, thus increasing health inequities. Here, the authors analyse data from 57,416 individuals of Bangladeshi and Pakistani ancestry in the UK-based Genes & Health cohort, finding ancestry-associated cancer risk variants and cancer-comorbidity pairs.

Here, the authors develop a dual-antigen (preS1-HBsAg) mRNA vaccine that elicits specific immune responses in a mouse model of chronic Hepatitis B virus (HBV) infection, that when combined with IFN-α has enhanced antiviral efficacy and immune memory.

Therapeutic options for patients with treatment-refractory metastatic urothelial carcinoma (mUC) are much needed. Here, the authors report the outcomes and translational analysis of the phase I/II ICRA trial evaluating whether paclitaxel plus tremelimumab (anti-CTLA-4) with or without durvalumab (anti-PD-L1) induces a tumor response in patients with mUC.

Vocal fold injury leads to fibrosis. Here, the authors identify oxidative stress as a key injury mechanism via single-cell sequencing and develop an in situ-forming hydrogel that provides physical shielding and redox regulation, restoring vibratory function.

Skin colour is known to confound optical devices, adversely impacting care for patients with darker skin. Here, the authors investigate this effect in photoacoustic imaging by characterising optical and acoustic mechanisms driving skin colour-dependent degradation in image quality and biomarker quantification.

A global analysis of over 7,000 climate-related disasters shows that human development is a stronger determinant of local disaster impacts than hazard intensity, and that inequality in human development amplifies risk in the least developed regions.

National-level technology diffusion rates vary substantially across 130 technologies and 5,990 time series. Newer technologies, as well as smaller, less materially intensive, and shorter-lived technologies, tend to be adopted more quickly.

This study uses visual intelligence to uncover a hidden genealogy of Singapore shophouses, showing that vernacular architecture evolved through dynamic cultural interaction rather than through a simple linear history.

This Perspective argues that violence against women remains persistently high, in some of the most socioeconomically advanced and gender-equal countries as well. Progress has stagnated and prevention efforts seem unable to reach younger generations.

Diesel use in remote Arctic communities could be reduced with hydrokinetic river turbines. The study identifies 325 viable communities globally and confirms feasibility in Nunavut, Canada, highlighting strong potential for cleaner local energy.