About: Amyloid beta

Property	Value
dbo:arm	q
dbo:band	21.2
dbo:chromosome	21
dbo:description	Protein (de) proteinë (sq) protéine (fr) proteïne (nl) بروتين (ar) péptido relacionado con la enfermedad de Alzheimer (es) group of peptides, several of which can form oligomeric cation-selective peptide channels (en) Proteiini (fi) amyloid (sv) アルツハイマー病患者の脳に見られるアミロイド斑の主成分たるペプチド (ja) 알츠하이머 병에 관여하는 아미노산 펩타이드 (ko)
dbo:entrezgene	351
dbo:hgncid	620
dbo:omim	104760 (xsd:integer)
dbo:refseq	NM_000484
dbo:symbol	APP AD1
dbo:thumbnail	wiki-commons:Special:FilePath/Abeta_2lfm.jpg?width=300
dbo:uniprot	P05067
dbo:wikiPageWikiLink	dbr:Intrinsically_unstructured_protein dbr:Endoplasmic_reticulum dbr:Golgi_apparatus dbr:Apomorphine dbr:Memantine dbr:Transcription_factor dbr:Crenezumab dbr:TPM21 dbr:Brain dbr:Calcium dbr:Bapineuzumab dbr:Secondary_structure dbr:Amino_acid dbr:Cancer dbr:Enzyme dbr:Inflammation dbr:Prion dbr:Protein_folding dbr:Alzheimer's_disease dbr:Proteolysis dbr:Colorectal_cancer dbr:Molecular_dynamics dbr:Homeostasis dbr:Immunotherapy dbr:Oligomer dbr:Alpha_secretase dbr:Kinase dbr:Lecanemab dbr:DNA_damage_(naturally_occurring) dbr:Ion_channel_hypothesis_of_Alzheimer's_disease dbr:Cholesterol dbr:Down_syndrome dbr:Lung_cancer dbr:Glycoprotein dbr:Peptide dbr:Beta-secretase_1 dbr:Amyloid_plaques dbr:Pittsburgh_compound_B dbr:Substrate_presentation dbr:Positron_emission_tomography dbr:White_matter dbr:Lipid_peroxidation dbr:Oxidative_stress dbr:Random_coil dbr:Enzyme_inhibitor dbr:Reactive_oxygen_species dbr:Semagacestat dbr:Tau_protein dbr:Transmembrane_protein dbr:Cyclin-dependent_kinase_5 dbr:Carbenoxolone dbr:Amyloid dbr:Thioflavin dbr:Solanezumab dbr:Aducanumab dbr:Ion_channel dbr:Apoptosis dbr:Cerebral_amyloid_angiopathy dbr:Etiology dbc:Amyloidosis dbr:Gamma_secretase dbr:Glymphatic_system dbr:Esophageal_cancer dbr:Tarenflurbil dbr:C-terminus dbr:ELISA dbr:Gantenerumab dbr:Neurite dbc:Peptides dbc:Alzheimer's_disease dbc:Biomarkers dbc:Molecular_neuroscience dbr:Sylvain_Lesné dbr:Dual_polarisation_interferometry dbr:Familial_Alzheimer_disease dbr:Antibodies dbr:Atomic_force_microscope dbr:Hereditary dbr:NMDA dbr:UB-311 dbr:Amyloid_precursor_protein dbr:PSEN1 dbr:NMR dbr:Cerebral_blood_vessel dbr:Nerve_cell dbr:Peptidase dbr:Chromosome_21_(human) dbr:BACE dbr:Deuterostomes dbr:Gamma-Secretase dbr:Immunostain dbr:Alpha_synuclein dbr:Amyloid_hypothesis dbr:Amyloid_plaque dbr:4-hydroxynonenal dbr:Hepatic_cancer dbr:Glucose_transporters dbr:Glutamate_transporters dbr:Parenchymal dbr:Replica_exchange dbr:Vibrational_spectroscopy dbr:CAD106 dbr:File:Cerebral_amyloid_angiopathy_-2b-_amyloid_beta_-_intermed_mag_-_cropped.jpg dbr:London_Mutation
dbp:altsymbols	AD1 (en)
dbp:arm	q (en)
dbp:band	21.200000 (xsd:double)
dbp:caption	A partially folded structure of amyloid beta in an aqueous environment (en) Processing of the amyloid precursor protein (en)
dbp:chromosome	21 (xsd:integer)
dbp:displayAuthors	6 (xsd:integer)
dbp:entrezgene	351 (xsd:integer)
dbp:hgncid	620 (xsd:integer)
dbp:interpro	IPR013803 (en)
dbp:membranomeSuperfamily	45 (xsd:integer)
dbp:name	Amyloid beta peptide (en) amyloid beta precursor protein (en)
dbp:nameListStyle	vanc (en)
dbp:omim	104760 (xsd:integer)
dbp:opmFamily	304 (xsd:integer)
dbp:opmProtein	2 (xsd:integer)
dbp:pfam	PF03494 (en)
dbp:refseq	NM_000484 (en)
dbp:scop	2 (xsd:integer)
dbp:symbol	dbr:Amyloid-beta_precursor_protein APP (en)
dbp:tcdb	1 (xsd:integer)
dbp:uniprot	P05067 (en)
dbp:width	300 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Infobox_protein dbt:Amyloidosis dbt:OMIM dbt:Infobox_protein_family dbt:Cn dbt:Cs1_config dbt:Further dbt:Reflist dbt:See_also dbt:Short_description dbt:Wiktionary
dct:subject	dbc:Amyloidosis dbc:Peptides dbc:Alzheimer's_disease dbc:Biomarkers dbc:Molecular_neuroscience
rdf:type	owl:Thing wikidata:Q206229 wikidata:Q8054 dbo:Biomolecule dbo:Biomolecule dbo:Protein dbo:Protein dbo:Protein umbel-rc:ProteinMolecule
rdfs:label	Amyloid beta (en) Beta amiloide (ca) Amyloid beta (cs) ببتيد بيتا النشواني (ar) Beta-Amyloid (de) Bêta-amyloïde (fr) Beta-amiloide (es) Betamiloide (it) アミロイドβ (ja) 아밀로이드 베타 (ko) Bèta-amyloïd (nl) Beta amiloide (pt) Бета-амилоиды (ru) Бета-амілоїд (uk) Beta-Amyloid (sv) Β淀粉样蛋白 (zh)
rdfs:seeAlso	dbr:Amyloid-beta_precursor_protein
owl:sameAs	freebase:Amyloid beta yago-res:Amyloid beta wikidata:Amyloid beta dbpedia-de:Amyloid beta dbpedia-es:Amyloid beta dbpedia-it:Amyloid beta dbpedia-nl:Amyloid beta dbpedia-fr:Amyloid beta dbpedia-he:Amyloid beta dbpedia-ja:Amyloid beta dbpedia-pt:Amyloid beta dbpedia-ru:Amyloid beta dbpedia-zh:Amyloid beta dbpedia-sv:Amyloid beta dbpedia-ko:Amyloid beta dbpedia-ca:Amyloid beta dbpedia-ar:Amyloid beta dbpedia-cs:Amyloid beta dbpedia-fa:Amyloid beta dbpedia-fi:Amyloid beta dbpedia-gl:Amyloid beta dbpedia-la:Amyloid beta dbpedia-mk:Amyloid beta dbpedia-th:Amyloid beta dbpedia-uk:Amyloid beta dbpedia-global:Amyloid beta
prov:wasDerivedFrom	wikipedia-en:Amyloid_beta?oldid=1310487450&ns=0
foaf:depiction	wiki-commons:Special:FilePath/APP_processing.png wiki-commons:Special:FilePath/Abeta_2lfm.jpg wiki-commons:Special:FilePath/Cerebral_amyloid_angi...oid_beta_-_intermed_mag_-_cropped.jpg
foaf:isPrimaryTopicOf	wikipedia-en:Amyloid_beta
foaf:name	amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) (en)
is dbo:knownFor of	dbr:David_M._Holtzman
is dbo:wikiPageRedirects of	dbr:A_beta dbr:A_beta_peptide dbr:Abeta dbr:Beta-amyloid dbr:Beta-amyloid dbr:Beta_amyloid dbr:Beta_amyloid dbr:Aβ dbr:B-amyloid dbr:Amyloid-Beta dbr:Amyloid-beta dbr:Amyloid-beta_peptide dbr:Amyloid-β dbr:Amyloid_B dbr:Amyloid_beta-peptides dbr:Amyloid_beta_peptide dbr:Amyloid_beta_protein dbr:Amyloid_β dbr:A-beta dbr:Islet_amyloid_precursor_protein dbr:Β-amyloid dbr:ΒA dbr:Β_amyloid
is dbo:wikiPageWikiLink of	dbr:Vascular_dementia dbr:Copper_in_biology dbr:Apomorphine dbr:HU-210 dbr:Neprilysin dbr:Peroxidase dbr:Pramlintide dbr:Colin_L._Masters dbr:Eicosanoid_receptor dbr:Cerebral_organoid dbr:A_beta dbr:A_beta_peptide dbr:Abeta dbr:Meningoencephalitis dbr:List_of_therapeutic_monoclonal_antibodies dbr:Agrin dbr:Alzheimer's_Disease_Neuroimaging_Initiative dbr:Parvulin dbr:JWH-133 dbr:Down_syndrome_research dbr:Urtė_Neniškytė dbr:Lipoxin dbr:Angiotensin-converting_enzyme dbr:Dementia_with_Lewy_bodies dbr:Plastoquinone dbr:Herpes_simplex_virus dbr:Human_alphaherpesvirus_1 dbr:Krtin_Nithiyanandam dbr:Meningeal_lymphatic_vessels dbr:Gambierol dbr:Cabernet_Sauvignon dbr:Alzheimer's_disease dbr:Intracranial_hemorrhage dbr:RNA_interference dbr:Brain-derived_neurotrophic_factor dbr:Alpha_sheet dbr:Complement_deficiency dbr:Computational_neurogenetic_modeling dbr:Superficial_siderosis dbr:2016_in_science dbr:Tara_Spires-Jones dbr:Priyanka_Joshi dbr:Insulin-degrading_enzyme dbr:Donanemab dbr:Alpha_secretase dbr:Lecanemab dbr:Neurodegenerative_disease dbr:Presenilin dbr:Slow-wave_sleep dbr:Cymserine dbr:Homotaurine dbr:Levuglandin dbr:Plasma_gelsolin dbr:Mission_Discovery dbr:Ion_channel_hypothesis_of_Alzheimer's_disease dbr:Down_syndrome dbr:Sleep_disorder dbr:Beta-secretase_1 dbr:Sleep_debt dbr:Amyloid_plaques dbr:Haemodynamic_response dbr:Molecular_neuroscience dbr:WIN_55,212-2 dbr:N-Acylethanolamine dbr:Epigenetics_of_neurodegenerative_diseases dbr:Visual_selective_attention_in_dementia dbr:Isolichenan dbr:Rosetta@home dbr:Amyloid-beta_precursor_protein dbr:Cathepsin dbr:Meldonium dbr:Proteinopathy dbr:Neuroscience_of_sleep dbr:Humanin dbr:RAGE_(receptor) dbr:APH-1 dbr:CHI3L1 dbr:Default_mode_network dbr:Granulocyte_colony-stimulating_factor dbr:Thioflavin dbr:Organ-limited_amyloidosis dbr:Solanezumab dbr:Aducanumab dbr:Asparagine_endopeptidase dbr:Sjors_Scheres dbr:YoungSoo_Kim dbr:Photo-induced_cross-linking_of_unmodified_proteins dbr:Li_Gan dbr:Reticulon dbr:QPNC-PAGE dbr:Cerebral_amyloid_angiopathy dbr:Li-Huei_Tsai dbr:Monoclonal_antibody_therapy dbr:P3_peptide dbr:2022_in_science dbr:G._Marius_Clore dbr:Gamma_wave dbr:Ka_Yee_Christina_Lee dbr:Gamma_secretase dbr:Nitromemantine dbr:Bradlee_Heckmann dbr:David_M._Holtzman dbr:Porphyromonas_gingivalis dbr:Macular_degeneration dbr:Transcytosis dbr:Intracerebral_hemorrhage dbr:Bulbocapnine dbr:Sacubitril/valsartan dbr:Granulin dbr:Monoamine_oxidase_B dbr:SNX8 dbr:TMEM106B dbr:VPS35 dbr:Protein_kinase_R dbr:Bennet_Omalu dbr:Neurotoxicity dbr:Sodium_oligomannate dbr:Experimental_models_of_Alzheimer's_disease dbr:Folding@home dbr:Alpha-7_nicotinic_receptor dbr:Biochemistry_of_Alzheimer's_disease dbr:Roskamp_Institute dbr:Hyperintensity dbr:Chemoproteomics dbr:Connie_C._Lu dbr:Phenserine dbr:Renã_A._S._Robinson dbr:HEPPS_(buffer) dbr:Prevention_of_dementia dbr:Ming_Tatt_Cheah dbr:Formyl_peptide_receptor_2 dbr:Maiken_Nedergaard dbr:Nicastrin dbr:Cognitive_genomics dbr:NLRP dbr:Extracellular_vesicle dbr:LRP1 dbr:Ataxin_1 dbr:Beta-amyloid dbr:Pyruvate_dehydrogenase_lipoamide_kinase_isozyme_1 dbr:Sylvain_Lesné dbr:Isabelle_Aubert dbr:TRPM2 dbr:Type_3_diabetes dbr:Neurotrophin_mimetics dbr:APBB2 dbr:APPBP1 dbr:BCL2L2 dbr:BCL3 dbr:CALHM1 dbr:DKK1 dbr:HIGD1A dbr:LILRA5 dbr:PEDF dbr:PLD3 dbr:TPI1 dbr:Neuroscience_of_aging dbr:Remote_ischemic_conditioning dbr:Czech_Brain_Ageing_Study dbr:Alev_Erisir dbr:LILRB2 dbr:Campenot_chamber dbr:Crystallopathy dbr:PSEN1 dbr:Beta_amyloid dbr:Beta-Methylamino-L-alanine dbr:PRNP dbr:Alzheimer's_disease_biomarkers dbr:Aβ dbr:B-amyloid dbr:Amyloid-Beta dbr:Amyloid-beta dbr:Amyloid-beta_peptide dbr:Amyloid-β dbr:Amyloid_B dbr:Amyloid_beta-peptides dbr:Amyloid_beta_peptide dbr:Amyloid_beta_protein dbr:Amyloid_β dbr:A-beta dbr:Islet_amyloid_precursor_protein dbr:Β-amyloid dbr:ΒA dbr:Β_amyloid
is dbp:target of	dbr:Bapineuzumab dbr:Donanemab dbr:Lecanemab dbr:Ponezumab dbr:Solanezumab dbr:Aducanumab dbr:Gantenerumab
is foaf:primaryTopic of	wikipedia-en:Amyloid_beta