About: Ribonuclease H

An Entity of Type: enzyme, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Enzyme family that degrades the RNA strand of RNA:DNA hybrids

Property	Value
dbo:description	enzyme family that degrades the RNA strand of RNA:DNA hybrids (en) enzym z klasy rybonukleaz (pl) Gruppe von Enzymen (Ribonukleasen), die RNA in DNA-RNA-Hybriden abbauen (de)
dbo:ecNumber	3.1.26.13 3.1.26.4
dbo:thumbnail	wiki-commons:Special:FilePath/RNase_H_fix.png?width=300
dbo:wikiPageExternalLink	https://www.ncbi.nlm.nih.gov/books/NBK1475/
dbo:wikiPageWikiLink	dbr:Basic_(chemistry) dbr:Hydroxyl dbr:Drug_target dbr:Human_endogenous_retrovirus dbr:Substrate_(chemistry) dbr:Aicardi–Goutières_syndrome dbr:Argonaute dbr:Endonuclease dbr:Exonuclease dbr:Retrotransposon dbr:Calcium dbr:Magnesium dbr:Manganese dbr:Virus dbr:Genetic_disorder dbr:Rare_disease dbr:Bioinformatics dbr:Calf_(animal) dbr:Catalysis dbr:DNA dbr:Enzyme dbr:Genome dbr:Hepatitis_B_virus dbr:Mammal dbr:Molecular_biology dbr:Neurology dbr:Reverse_transcriptase dbr:Protein_folding dbr:Base_pair dbr:DNA_replication dbr:Cas9 dbr:Pyrococcus_abyssi dbr:Archaea dbr:Bacteria dbr:Conceptual_model dbr:Eukaryote dbr:HIV dbr:HIV/AIDS dbr:Prokaryote dbr:RNA dbr:Escherichia_coli dbr:Mitochondrial_DNA dbr:Histidine dbr:Chelation dbr:Pathogen dbr:Thymus dbr:Murine_leukemia_virus dbr:Human_genome dbr:Protein_purification dbr:Sequence_motif dbr:Spliceosome dbr:Nucleotide_excision_repair dbr:Protein_trimer dbr:R-loop dbr:Cell_nucleus dbr:Lethal_allele dbr:Mitochondrial_disease dbr:Homo_sapiens dbr:Piwi dbr:Chemotype dbr:Horizontal_gene_transfer dbr:Hydrolysis dbr:Protein_structure dbr:Knockout_mouse dbr:Protein_domain dbr:Surface_plasmon_resonance dbr:Active_site dbr:Enzyme_inhibitor dbr:Nuclease dbr:Ribonucleotide dbr:Gene_knockout dbr:Sense_(molecular_biology) dbr:Prp8 dbr:DsDNA-RT_virus dbr:RNA_virus dbr:Chronic_progressive_external_ophthalmoplegia dbr:Dermatology dbr:Oncovirus dbr:Retrovirus dbr:Transposase dbr:Essential_gene dbr:Reverse_transcription dbr:Complementary_DNA dbr:N-terminus dbr:Mechanism_of_action dbr:Protein_isoform dbr:Phosphate dbr:Long_terminal_repeat dbr:Hot_start_PCR dbr:Retroviral_ribonuclease_H dbr:ADAR dbr:Processivity dbr:C-terminus dbr:Ribonuclease_inhibitor dbr:Peter_Hausen dbc:EC_3.1.26 dbr:Double_helix dbc:Molecular_biology dbr:MDA5 dbr:SAMHD1 dbc:Ribonucleases dbr:PKa dbr:ERVK6 dbr:RNASEH1 dbr:RNASEH2A dbr:RNASEH2B dbr:RNASEH2C dbr:TREX1 dbr:Embryogenesis dbr:Human_immunodeficiency_virus dbr:Mitochondria dbr:RNase_H-dependent_PCR dbr:E._coli dbr:Mitochondrial_genome dbr:HIV-1 dbr:DNA-dependent_DNA_polymerase dbr:Glutamate dbr:TRNA dbr:Protein-protein_interaction dbr:Archaeon dbr:Holliday_junction_resolvase dbr:Hyperthermophilic dbr:Laboratory_reagent dbr:Antiretroviral dbr:Aspartate dbr:3' dbr:5' dbr:Domains_of_life dbr:PCNA dbr:Phosphodiester dbr:Phylogenetic_relationship dbr:Chemical_mechanism dbr:Mitochondrial_targeting_sequence dbr:Retroviral dbr:Retroviral_integrase dbr:Reverse-transcriptase_inhibitors dbr:Type_I_interferon dbr:Nucleotide_sequence dbr:RNA-dependent_DNA_polymerase dbr:RNA_primer dbr:RNase_T dbr:TATA_box_binding_protein dbr:Okazaki_fragment dbr:S._cerevisiae dbr:Α-helices dbr:Β-sheet dbr:Sequence_identity dbr:File:3puf_rnaseH2_AGS_mutations.png dbr:File:1hys_hiv_RT_highlight_rnh.png dbr:File:RNaseH_active_site.svg dbr:File:Ribonuclease_H_structure_comparison.png
dbp:caption	Crystallographic structure of E. coli RNase HI. (en)
dbp:casNumber	9050 (xsd:integer)
dbp:ecNumber	3.100000 (xsd:double)
dbp:goCode	452 (xsd:integer)
dbp:interpro	IPR002156 (en) IPR024567 (en)
dbp:name	retroviral ribonuclease H (en) ribonuclease H (en)
dbp:pfam	PF00075 (en) PF01351 (en)
dbp:pfamClan	CL0219 (en)
dbp:prosite	PS50879 (en)
dbp:symbol	RNase H (en) RNase HII (en)
dbp:wikiPageUsesTemplate	dbt:Enzyme dbt:Infobox_protein_family dbt:Enzymes dbt:MeshName dbt:PDB dbt:Portal_bar dbt:Reflist dbt:See_also dbt:Short_description dbt:DNA_replication dbt:Esterases
dct:subject	dbc:EC_3.1.26 dbc:Ribonucleases
gold:hypernym	dbr:Family
rdf:type	owl:Thing wikidata:Q206229 wikidata:Q8047 dbo:Biomolecule dbo:Biomolecule dbo:Enzyme dbo:Enzyme dbo:Enzyme
rdfs:label	Ribonuclease H (en) رناز هتش (ar) Ribonucleasa H (es) Ribonukleasen H (de) Ribonucléase H (fr) リボヌクレアーゼH (ja) Ribonuclease H (pt) РНКаза H (ru) 核糖核酸酶H (zh)
rdfs:seeAlso	dbr:Retroviral_ribonuclease_H
owl:sameAs	freebase:Ribonuclease H yago-res:Ribonuclease H http://www4.wiwiss.fu-berlin.de/drugbank/resource/targets/3497 http://www4.wiwiss.fu-berlin.de/drugbank/resource/targets/3511 http://www4.wiwiss.fu-berlin.de/drugbank/resource/targets/5448 wikidata:Ribonuclease H dbpedia-de:Ribonuclease H dbpedia-es:Ribonuclease H dbpedia-fr:Ribonuclease H dbpedia-ja:Ribonuclease H dbpedia-pt:Ribonuclease H dbpedia-ru:Ribonuclease H dbpedia-zh:Ribonuclease H dbpedia-vi:Ribonuclease H dbpedia-ar:Ribonuclease H dbpedia-gl:Ribonuclease H dbpedia-sh:Ribonuclease H dbpedia-sr:Ribonuclease H dbpedia-global:Ribonuclease H
prov:wasDerivedFrom	wikipedia-en:Ribonuclease_H?oldid=1302929299&ns=0
foaf:depiction	wiki-commons:Special:FilePath/3puf_rnaseH2_AGS_mutations.png wiki-commons:Special:FilePath/1hys_hiv_RT_highlight_rnh.png wiki-commons:Special:FilePath/RNaseH_active_site.svg wiki-commons:Special:FilePath/RNase_H_fix.png wiki-commons:Special:FilePath/Ribonuclease_H_structure_comparison.png
foaf:isPrimaryTopicOf	wikipedia-en:Ribonuclease_H
foaf:name	retroviral ribonuclease H (en) ribonuclease H (en)
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is foaf:primaryTopic of	wikipedia-en:Ribonuclease_H