10 ENGLISH BOOKS RELATING TO «BLEOMYCIN»
Discover the use of
bleomycin in the following bibliographical selection. Books relating to
bleomycin and brief extracts from same to provide context of its use in English literature.
1
Fundamental and Clinical Studies of
Bleomycin
Consists of the proceedings of international conference and symposia.
Bleomycin exerts its toxic effects where it concentrates: in the skin, mucous
membranes, and lungs. The lungs and skin are particularly susceptible to
bleomycin toxicity, perhaps because of the paucity of the inactivating enzyme,
bleomycin ...
Sai-Ching Jim Yeung, Carmen P. Escalante, 2002
3
Principles and Practice of Gynecologic Oncology
When complexed with ferrous iron, bleomycin becomes a potent oxidase,
producing DNA strand breaks by oxygen free radicals. Its unique mechanism of
action is schedule dependent and cell cycle dependent for the G2 phase. The
oxygen ...
4
Bleomycin: Chemical, Biochemical, and Biological Aspects: ...
With contributions by numerous experts
5
Electrochemotherapy, Electrogenetherapy, and Transdermal ...
Biological Characteristics of Bleomycin 3.1.1. Bleomycin Is a Nonpermeant Drug
Bleomycin is an excellent example of a nonpermeant cytotoxic drug (21,29,32). It
was demonstrated in vitro that bleomycin cannot diffuse through the plasma ...
Mark J. Jaroszeski, Richard Heller, Richard Gilbert (PhD.), 2000
6
Oncology: An Evidence-Based Approach
Reported manifestations of bleomycin-induced pulmonary toxicity. Chronic
interstitial pneumonia/chronic fibrosis Acute interstitial pneumonia/acute fibrosis
Bronchiolitis obliterans-organizing pneumonia Hypersensitivity pneumonitis
Single or ...
Alfred E. Chang, Patricia A. Ganz, Daniel F. Hayes, 2007
7
Principles and Practice of Gynecologic Oncology
Bleomycin (Blenoxane), an antineoplastic, is a mixture of complex glycopeptides
originally isolated from a strain of the fungus Streptomyces verticillus. The
primary components are bleomycins A2 and B2. The family of bleomycin
glycopeptides ...
Richard R. Barakat, Maurie Markman, Marcus Randall, 2009
8
Studies Toward Understanding the Mechanism of
Bleomycin: ...
Figure 1.4. Generation of activated bleomycin in vivo Bleomycin Bleomycin-Cu(II)
Cu(II) transporter? Cellular Membrane Bleomycin-Cu(II) Cu(II) Nucleus DNA
Damage activated bleomycin Bleomycin Bleomycin-Fe(II) Bleomycin-Fe(III)-OOH
...
9
Cancer Chemotherapy and Biotherapy: Principles and Practice
The neutral cysteine protease bleomycin hydrolase is essential for epidermal
integrity and bleomycin resistance. Proc Natl Acad Sci USA 1999;96:4680. 49. de
Haas EC, Zwart N, Meijer C, et al. Variation in bleomycin hydrolase gene is ...
Bruce A. Chabner, Dan L. Longo, 2011
Chem. Rev. 87:1107 (1987). 139. A. P. Grollman: "Base propenals and the
toxicity of bleomycin," in Organ Directed Toxicities of Anticancer Drugs, ed. by
M. P. Hacker, J. S. Lazo, and T. R. Tritton. Boston: Martinus Nijhoff Pub., 1987, pp.
79-90.
10 NEWS ITEMS WHICH INCLUDE THE TERM «BLEOMYCIN»
Find out what the national and international press are talking about and how the term
bleomycin is used in the context of the following news items.
CNIO researchers show that telomeres are linked to the origins of …
To induce damage they chose bleomycin, a drug that affects the genetic material of cells and inhibits cell division when administered in high ... «Medical Xpress, Jul 15»
Bleomycin, Vincristine Discontinuation Doesn't Affect Efficacy in …
In patients with advanced Hodgkin lymphoma (HL), bleomycin and vincristine cause significant toxicity that leads to dose reaction or ... «Cancer Therapy Advisor, Jun 15»
Interim FDG-PET Scans Enable Response-Adapted Therapy in …
Of particular note, it was demonstrated that pulmonary toxicity could be decreased without loss of efficacy by omitting bleomycin from ABVD ... «OncLive, Jun 15»
Clinical Conundrums
... IIA Hodgkin lymphoma (HL) and negative positron emission tomography (PET) scanning after 3 cycles of doxorubicin, bleomycin, vinblastine, ... «Clinical Oncology News, Jun 15»
Seattle Genetics Announces Multiple ADCETRIS® (Brentuximab …
ADCETRIS is contraindicated with concomitant bleomycin due to pulmonary toxicity (e.g. interstitial infiltration and/or inflammation). Warnings ... «PharmiWeb.com, Jun 15»
GDNF as collateral damage of prostate cancer chemotherapy
... agents (bleomycin, mitoxantrone, radiation and docetaxel). Importantly, GDNF expression was also elevated in cancer-associated fibroblasts ... «Fred Hutch News Service, Jun 15»
Medical Oxygen Systems Market – Global Industry Analysis and …
... in patients administrating antibiotics such as nitrofurantoin bleomycin and amiodarone. Sometimes, compressed medical oxygen toxicity may ... «Medgadget.com, Jun 15»
Family of cancer victim sues Concord doctor for failing to notice fatal …
Doctors determined the direct cause was not the cancer, but rather a side effect of one of the chemotherapy drugs – Bleomycin. «Concord Monitor, Jun 15»
Autophagy protects against lung inflammation, fibrosis
In this study, when mice deficient in autophagy were challenged with the drug bleomycin, known to cause pulmonary fibrosis, they had more ... «Baylor College of Medicine News, Jun 15»
RestorGenex Presents Results of Experimental Idiopathic …
Results from a study that assessed the efficacy of RES-529 in a 10-day in vivo mouse model of bleomycin-induced pulmonary fibrosis showed ... «Lung Disease News, May 15»
