Evidence-Based GI
For clinicians, ASTRO provides the data needed to determine which patients may reasonably avoid infusion-based therapy and begin treatment entirely at home.
For patients and providers trying to understand the benefits and risks of CRC screening via colonoscopy or FIT, the SCREESCO study provides valuable data we can share with our patients to help them make informed decisions. An important caveat in extrapolating the FIT data from this study to patients in the United States is to highlight that while the SCREESCO trial used a two-stool FIT protocol, we typically perform annual single-sample testing in the United States.
This trial tempers enthusiasm for immediate widespread adoption of AI-assisted EGD as a tool to improve gastric neoplasm detection rates in high-volume, experienced endoscopy settings. However, the significant reduction in blind spots supports the use of AI as a quality monitoring tool during EGD.
One of the most notable observations is the unexpectedly high burden of CKD among liver transplant recipients. The EVEROLIVER registry makes a compelling case for early reduction in calcineurin inhibitors and conversion to mTOR inhibitors, while conversion after 12 months provided no benefit. These data suggest a narrow therapeutic window during which renal recovery remains achievable.
I follow the USMSTF for CRC recommendations for post polypectomy which currently suggest a 5-year follow up for these patients. These data support that recommendation by demonstrating that the risk for these patients is elevated at second surveillance colonoscopy and is independent of known risk factors as well as the adenoma detection rates of the endoscopists performing the colonoscopies.
Appendectomy as an adjunct to ongoing advanced therapy achieved clinical remission without therapy failure in 33% of patients at 12 months, compared with 12% with JAK inhibitor therapy alone in patients with moderately to severely active UC.
The ACG HE guideline is the first to consolidate diagnosis, management, recurrence prevention, nutrition, TIPS-related HE, and transplant access into a unified, GRADE-based framework.
This study demonstrates a more dynamic process as being potentially successful and easily adoptable throughout the world. Namely, by having patients able to interact with an application at home prior to endoscopy they can alert offices to difficulty with preparation or only present to endoscopy suites when their preparation has completed.
Using data from examinations using all indications rather than screening exams alone can be beneficial by allowing a larger sample size, which may provide a more accurate assessment of an endoscopist’s overall performance. It can also mitigate potential gaming by endoscopists to manipulate their metrics.
EHR Templates Improve Colonoscopy Surveillance Accuracy Timothy Yen, MD Assistant Professor, Loma Linda University Health, Loma Linda, CA This article…
